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secHsp70 as a tool to approach amyloid-β42 and other extracellular amyloids

Self-association of amyloidogenic proteins is the main pathological trigger in a wide variety of neurodegenerative disorders. These aggregates are deposited inside or outside the cell due to hereditary mutations, environmental exposures or even normal aging. Cumulative evidence indicates that the he...

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Detalles Bibliográficos
Autores principales: De Mena, Lorena, Chhangani, Deepak, Fernandez-Funez, Pedro, Rincon-Limas, Diego E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552267/
https://www.ncbi.nlm.nih.gov/pubmed/28165856
http://dx.doi.org/10.1080/19336934.2017.1291104