Cargando…
Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice
Visceral adiposity confers significant risk for developing metabolic disease in obesity whereas preferential expansion of subcutaneous white adipose tissue (WAT) appears protective. Unlike subcutaneous WAT, visceral WAT is resistant to adopting a protective thermogenic phenotype characterized by the...
Autores principales: | Hepler, Chelsea, Shao, Mengle, Xia, Jonathan Y, Ghaben, Alexandra L, Pearson, Mackenzie J, Vishvanath, Lavanya, Sharma, Ankit X, Morley, Thomas S, Holland, William L, Gupta, Rana K |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552276/ https://www.ncbi.nlm.nih.gov/pubmed/28722653 http://dx.doi.org/10.7554/eLife.27669 |
Ejemplares similares
-
Sorting out adipocyte precursors and their role in physiology and disease
por: Hepler, Chelsea, et al.
Publicado: (2017) -
Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice
por: Hepler, Chelsea, et al.
Publicado: (2018) -
De novo adipocyte differentiation from Pdgfrβ(+) preadipocytes protects against pathologic visceral adipose expansion in obesity
por: Shao, Mengle, et al.
Publicado: (2018) -
ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes
por: Shao, Mengle, et al.
Publicado: (2021) -
Cold-responsive adipocyte progenitors couple adrenergic signaling to immune cell activation to promote beige adipocyte accrual
por: Shan, Bo, et al.
Publicado: (2021)