Methyl pyruvate protects a normal lung fibroblast cell line from irinotecan-induced cell death: Potential use as adjunctive to chemotherapy

The Warburg Effect, characterized by increased rate of glycolysis even under normoxic conditions, is one of the hallmarks of cancer. Relatively lower oxidative phosphorylation (OXPHOS) is also a characteristic feature in cancer cells. We hypothesized that interference with this phenomenon, by introd...

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Detalles Bibliográficos
Autores principales: Monchusi, Bernice, Ntwasa, Monde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552298/
https://www.ncbi.nlm.nih.gov/pubmed/28797070
http://dx.doi.org/10.1371/journal.pone.0182789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552298/
https://www.ncbi.nlm.nih.gov/pubmed/28797070
http://dx.doi.org/10.1371/journal.pone.0182789

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