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Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles

Parkinson's disease (PD) is a progressive and currently incurable neurological disorder characterised by the loss of midbrain dopaminergic neurons and the accumulation of aggregated alpha-synuclein (a-syn). Oligomeric a-syn is proposed to play a central role in spreading protein aggregation in...

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Detalles Bibliográficos
Autores principales:	Doucet, Marika, El-Turabi, Aadil, Zabel, Franziska, Hunn, Benjamin H.M., Bengoa-Vergniory, Nora, Cioroch, Milena, Ramm, Mauricio, Smith, Amy M., Gomes, Ariane Cruz, Cabral de Miranda, Gustavo, Wade-Martins, Richard, Bachmann, Martin F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552317/ https://www.ncbi.nlm.nih.gov/pubmed/28797124 http://dx.doi.org/10.1371/journal.pone.0181844

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