Arginine metabolic endotypes related to asthma severity

AIMS: Arginine metabolism via inducible nitric oxide synthase (iNOS) and arginase 2 (ARG2) is higher in asthmatics than in healthy individuals. We hypothesized that a sub-phenotype of asthma might be defined by the magnitude of arginine metabolism categorized on the basis of high and low fraction of...

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Detalles Bibliográficos
Autores principales: Xu, Weiling, Comhair, Suzy A. A., Janocha, Allison J., Lara, Abigail, Mavrakis, Lori A., Bennett, Carole D., Kalhan, Satish C., Erzurum, Serpil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552347/
https://www.ncbi.nlm.nih.gov/pubmed/28797075
http://dx.doi.org/10.1371/journal.pone.0183066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552347/
https://www.ncbi.nlm.nih.gov/pubmed/28797075
http://dx.doi.org/10.1371/journal.pone.0183066

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