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Arginine metabolic endotypes related to asthma severity

AIMS: Arginine metabolism via inducible nitric oxide synthase (iNOS) and arginase 2 (ARG2) is higher in asthmatics than in healthy individuals. We hypothesized that a sub-phenotype of asthma might be defined by the magnitude of arginine metabolism categorized on the basis of high and low fraction of...

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Detalles Bibliográficos
Autores principales:	Xu, Weiling, Comhair, Suzy A. A., Janocha, Allison J., Lara, Abigail, Mavrakis, Lori A., Bennett, Carole D., Kalhan, Satish C., Erzurum, Serpil C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552347/ https://www.ncbi.nlm.nih.gov/pubmed/28797075 http://dx.doi.org/10.1371/journal.pone.0183066

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