Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study

Tumor necrosis factor receptor type 1 (TNFR1) is associated with kidney disease and mortality risk in various populations [1], [2]. We evaluated associations of TNFR1 with mortality and mediators of this relationship in doi: 10.1016/j.atherosclerosis.2017.05.021. Whether or not these associations ar...

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Detalles Bibliográficos
Autores principales: Park, Meyeon, Maristany, Daniela, Huang, Debbie, Shlipak, Michael G., Whooley, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Medicine and Dentistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552376/
https://www.ncbi.nlm.nih.gov/pubmed/28831402
http://dx.doi.org/10.1016/j.dib.2017.07.048
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author Park, Meyeon
Maristany, Daniela
Huang, Debbie
Shlipak, Michael G.
Whooley, Mary
author_facet Park, Meyeon
Maristany, Daniela
Huang, Debbie
Shlipak, Michael G.
Whooley, Mary
author_sort Park, Meyeon
collection PubMed
description Tumor necrosis factor receptor type 1 (TNFR1) is associated with kidney disease and mortality risk in various populations [1], [2]. We evaluated associations of TNFR1 with mortality and mediators of this relationship in doi: 10.1016/j.atherosclerosis.2017.05.021. Whether or not these associations are influenced by age, gender, or baseline kidney function are not known. We evaluated associations of TNFR1 levels with measures of kidney function stratifying by these variables. Our outcomes included estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m(2), albumin to creatinine ratio (ACR) >30 mg/g, and rapid kidney function loss, defined as a change in eGFR of greater than 3% per year.
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spelling pubmed-55523762017-08-22 Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study Park, Meyeon Maristany, Daniela Huang, Debbie Shlipak, Michael G. Whooley, Mary Data Brief Medicine and Dentistry Tumor necrosis factor receptor type 1 (TNFR1) is associated with kidney disease and mortality risk in various populations [1], [2]. We evaluated associations of TNFR1 with mortality and mediators of this relationship in doi: 10.1016/j.atherosclerosis.2017.05.021. Whether or not these associations are influenced by age, gender, or baseline kidney function are not known. We evaluated associations of TNFR1 levels with measures of kidney function stratifying by these variables. Our outcomes included estimated glomerular filtration rate (eGFR) < 60 ml/min/1.73 m(2), albumin to creatinine ratio (ACR) >30 mg/g, and rapid kidney function loss, defined as a change in eGFR of greater than 3% per year. Elsevier 2017-07-26 /pmc/articles/PMC5552376/ /pubmed/28831402 http://dx.doi.org/10.1016/j.dib.2017.07.048 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Medicine and Dentistry
Park, Meyeon
Maristany, Daniela
Huang, Debbie
Shlipak, Michael G.
Whooley, Mary
Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study
title Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study
title_full Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study
title_fullStr Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study
title_full_unstemmed Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study
title_short Associations of TNFR1 with kidney function outcomes by age, gender, and baseline kidney function status: Data from the Heart and Soul Study
title_sort associations of tnfr1 with kidney function outcomes by age, gender, and baseline kidney function status: data from the heart and soul study
topic Medicine and Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552376/
https://www.ncbi.nlm.nih.gov/pubmed/28831402
http://dx.doi.org/10.1016/j.dib.2017.07.048
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