Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinase 4 Triggers Glioblastoma Progression

Glioblastoma (GBM) is the most common primary brain tumor and has a dismal prognosis. Amplification of chromosome 12q13–q15 [Cyclin-dependent kinase 4 (CDK4) amplicon] is frequently observed in numerous human cancers including GBM. Phosphoinositide 3-kinase enhancer (PIKE) is a group of GTP-binding...

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Detalles Bibliográficos
Autores principales: Qi, Qi, Kang, Seong-Su, Zhang, Shuai, Pham, Cau, Fu, Haian, Brat, Daniel J., Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552418/
https://www.ncbi.nlm.nih.gov/pubmed/28368413
http://dx.doi.org/10.1038/onc.2017.67

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552418/
https://www.ncbi.nlm.nih.gov/pubmed/28368413
http://dx.doi.org/10.1038/onc.2017.67

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