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Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinase 4 Triggers Glioblastoma Progression

Glioblastoma (GBM) is the most common primary brain tumor and has a dismal prognosis. Amplification of chromosome 12q13–q15 [Cyclin-dependent kinase 4 (CDK4) amplicon] is frequently observed in numerous human cancers including GBM. Phosphoinositide 3-kinase enhancer (PIKE) is a group of GTP-binding...

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Detalles Bibliográficos
Autores principales:	Qi, Qi, Kang, Seong-Su, Zhang, Shuai, Pham, Cau, Fu, Haian, Brat, Daniel J., Ye, Keqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552418/ https://www.ncbi.nlm.nih.gov/pubmed/28368413 http://dx.doi.org/10.1038/onc.2017.67

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