Timing of Developmental Reduction in Epithelial Glutathione Redox Potential is Associated with Increased Epithelial Proliferation in the Immature Murine Intestine

BACKGROUND: The intracellular redox potential of the glutathione (GSH)/glutathione disulfide (GSSG) couple regulates cellular processes. In vitro studies indicate that a reduced GSH/GSSG redox potential favors proliferation, while a more oxidized redox potential favors differentiation. Intestinal gr...

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Detalles Bibliográficos
Autores principales: Reid, Graham K., Berardinelli, Andrew J., Ray, Laurie, Jackson, Arena R., Neish, Andrew S., Hansen, Jason M., Denning, Patricia W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552438/
https://www.ncbi.nlm.nih.gov/pubmed/28288146
http://dx.doi.org/10.1038/pr.2017.49

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