Establishment of a tobacco BY2 cell line devoid of plant‐specific xylose and fucose as a platform for the production of biotherapeutic proteins

Plant‐produced glycoproteins contain N‐linked glycans with plant‐specific residues of β(1,2)‐xylose and core α(1,3)‐fucose, which do not exist in mammalian‐derived proteins. Although our experience with two enzymes that are used for enzyme replacement therapy does not indicate that the plant sugar r...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanania, Uri, Ariel, Tami, Tekoah, Yoram, Fux, Liat, Sheva, Maor, Gubbay, Yehuda, Weiss, Mara, Oz, Dina, Azulay, Yaniv, Turbovski, Albina, Forster, Yehava, Shaaltiel, Yoseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552476/
https://www.ncbi.nlm.nih.gov/pubmed/28160363
http://dx.doi.org/10.1111/pbi.12702

Ejemplares similares

Ejemplares similares