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Transcriptional hallmarks of cancer cell lines reveal an emerging role of branched chain amino acid catabolism

A comparative analysis between cancer cell lines and healthy dividing cells was performed using data (289 microarrays and 50 RNA-seq samples) from 100 different cancer cell lines and 6 types of healthy stem cells. The analysis revealed two large-scale transcriptional events that characterize cancer...

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Detalles Bibliográficos
Autores principales: Antanavičiūtė, Ieva, Mikalayeva, Valeryia, Ceslevičienė, Ieva, Milašiūtė, Gintarė, Skeberdis, Vytenis Arvydas, Bordel, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552680/
https://www.ncbi.nlm.nih.gov/pubmed/28798381
http://dx.doi.org/10.1038/s41598-017-08329-8