Biodegradable Carriers for Delivery of VEGF Plasmid DNA for the Treatment of Critical Limb Ischemia

The safe and efficient delivery of therapeutic nucleic acid is a prerequisite for an effective DNA therapy. In this study, we condensed the low molecular weight polyethylenimine (PEI, 1.8k Da) with 2,6-pyridinedicarboxaldehyde (PDA), both of which are degradable in vivo, to synthesize a biodegradabl...

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Detalles Bibliográficos
Autores principales: Liu, Guang, Fang, Zhiwei, Yuan, Minglu, Li, Weimin, Yang, Yunqi, Jiang, Mier, Ouyang, Yuanming, Yuan, Weien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552722/
https://www.ncbi.nlm.nih.gov/pubmed/28848442
http://dx.doi.org/10.3389/fphar.2017.00528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552722/
https://www.ncbi.nlm.nih.gov/pubmed/28848442
http://dx.doi.org/10.3389/fphar.2017.00528

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