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Mass & secondary structure propensity of amino acids explain their mutability and evolutionary replacements
Why is an amino acid replacement in a protein accepted during evolution? The answer given by bioinformatics relies on the frequency of change of each amino acid by another one and the propensity of each to remain unchanged. We propose that these replacement rules are recoverable from the secondary s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552740/ https://www.ncbi.nlm.nih.gov/pubmed/28798365 http://dx.doi.org/10.1038/s41598-017-08041-7 |