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Jagged1 Is Altered in Alzheimer's Disease and Regulates Spatial Memory Processing

Notch signaling plays an instrumental role in hippocampus-dependent memory formation and recent evidence indicates a displacement of Notch1 and a reduction its activity in hippocampal and cortical neurons from Alzheimer's disease (AD) patients. As Notch activation depends on ligand availability...

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Detalles Bibliográficos
Autores principales:	Marathe, Swananda, Jaquet, Muriel, Annoni, Jean-Marie, Alberi, Lavinia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552758/ https://www.ncbi.nlm.nih.gov/pubmed/28848392 http://dx.doi.org/10.3389/fncel.2017.00220

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