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ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells

FRET and BRET approaches are well established for detecting ligand induced GPCR-G protein interactions in cells. Currently, FRET/BRET assays rely on co-expression of GPCR and G protein, and hence depend on the stoichiometry and expression levels of the donor and acceptor probes. On the other hand, G...

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Detalles Bibliográficos
Autores principales:	Malik, Rabia U., Dysthe, Matthew, Ritt, Michael, Sunahara, Roger K., Sivaramakrishnan, Sivaraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552854/ https://www.ncbi.nlm.nih.gov/pubmed/28798477 http://dx.doi.org/10.1038/s41598-017-08029-3

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