The Bitter Taste Receptor TAS2R16 Achieves High Specificity and Accommodates Diverse Glycoside Ligands by using a Two-faced Binding Pocket

Although bitter taste receptors (TAS2Rs) are important for human health, little is known of the determinants of ligand specificity. TAS2Rs such as TAS2R16 help define gustatory perception and dietary preferences that ultimately influence human health and disease. Each TAS2R must accommodate a broad...

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Detalles Bibliográficos
Autores principales: Thomas, Anu, Sulli, Chidananda, Davidson, Edgar, Berdougo, Eli, Phillips, Morganne, Puffer, Bridget A., Paes, Cheryl, Doranz, Benjamin J., Rucker, Joseph B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552880/
https://www.ncbi.nlm.nih.gov/pubmed/28798468
http://dx.doi.org/10.1038/s41598-017-07256-y

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