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Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria
Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genom...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552975/ https://www.ncbi.nlm.nih.gov/pubmed/28798166 http://dx.doi.org/10.1128/genomeA.00653-17 |
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author | Crofts, Terence S. Wang, Bin Spivak, Aaron Gianoulis, Tara A. Forsberg, Kevin J. Gibson, Molly K. Johnsky, Lauren A. Broomall, Stacey M. Rosenzweig, C. Nicole Skowronski, Evan W. Gibbons, Henry S. Sommer, Morten O. A. Dantas, Gautam |
author_facet | Crofts, Terence S. Wang, Bin Spivak, Aaron Gianoulis, Tara A. Forsberg, Kevin J. Gibson, Molly K. Johnsky, Lauren A. Broomall, Stacey M. Rosenzweig, C. Nicole Skowronski, Evan W. Gibbons, Henry S. Sommer, Morten O. A. Dantas, Gautam |
author_sort | Crofts, Terence S. |
collection | PubMed |
description | Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genomes encode multiple β-lactamases, although their antibiotic catabolic pathways remain enigmatic. |
format | Online Article Text |
id | pubmed-5552975 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-55529752017-08-25 Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria Crofts, Terence S. Wang, Bin Spivak, Aaron Gianoulis, Tara A. Forsberg, Kevin J. Gibson, Molly K. Johnsky, Lauren A. Broomall, Stacey M. Rosenzweig, C. Nicole Skowronski, Evan W. Gibbons, Henry S. Sommer, Morten O. A. Dantas, Gautam Genome Announc Prokaryotes Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genomes encode multiple β-lactamases, although their antibiotic catabolic pathways remain enigmatic. American Society for Microbiology 2017-08-10 /pmc/articles/PMC5552975/ /pubmed/28798166 http://dx.doi.org/10.1128/genomeA.00653-17 Text en Copyright © 2017 Crofts et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Prokaryotes Crofts, Terence S. Wang, Bin Spivak, Aaron Gianoulis, Tara A. Forsberg, Kevin J. Gibson, Molly K. Johnsky, Lauren A. Broomall, Stacey M. Rosenzweig, C. Nicole Skowronski, Evan W. Gibbons, Henry S. Sommer, Morten O. A. Dantas, Gautam Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria |
title | Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria |
title_full | Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria |
title_fullStr | Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria |
title_full_unstemmed | Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria |
title_short | Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria |
title_sort | draft genome sequences of three β-lactam-catabolizing soil proteobacteria |
topic | Prokaryotes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552975/ https://www.ncbi.nlm.nih.gov/pubmed/28798166 http://dx.doi.org/10.1128/genomeA.00653-17 |
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