Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014

A novel variant of the plasmid-borne colistin resistance gene mcr-3 was detected on an IncHI2 plasmid in an ST131 CTX-M-55-producing Escherichia coli isolate from a Danish patient with bloodstream infection in 2014. The discovery of novel plasmid-borne genes conferring resistance to colistin is of s...

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Autores principales: Roer, Louise, Hansen, Frank, Stegger, Marc, Sönksen, Ute Wolff, Hasman, Henrik, Hammerum, Anette M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2017
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553058/
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.31.30584
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author Roer, Louise
Hansen, Frank
Stegger, Marc
Sönksen, Ute Wolff
Hasman, Henrik
Hammerum, Anette M
author_facet Roer, Louise
Hansen, Frank
Stegger, Marc
Sönksen, Ute Wolff
Hasman, Henrik
Hammerum, Anette M
author_sort Roer, Louise
collection PubMed
description A novel variant of the plasmid-borne colistin resistance gene mcr-3 was detected on an IncHI2 plasmid in an ST131 CTX-M-55-producing Escherichia coli isolate from a Danish patient with bloodstream infection in 2014. The discovery of novel plasmid-borne genes conferring resistance to colistin is of special interest since colistin has reemerged as an important drug in the treatment of infections with multidrug-resistant Gram-negative bacteria.
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spelling pubmed-55530582017-08-28 Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014 Roer, Louise Hansen, Frank Stegger, Marc Sönksen, Ute Wolff Hasman, Henrik Hammerum, Anette M Euro Surveill Rapid Communication A novel variant of the plasmid-borne colistin resistance gene mcr-3 was detected on an IncHI2 plasmid in an ST131 CTX-M-55-producing Escherichia coli isolate from a Danish patient with bloodstream infection in 2014. The discovery of novel plasmid-borne genes conferring resistance to colistin is of special interest since colistin has reemerged as an important drug in the treatment of infections with multidrug-resistant Gram-negative bacteria. European Centre for Disease Prevention and Control (ECDC) 2017-08-03 /pmc/articles/PMC5553058/ http://dx.doi.org/10.2807/1560-7917.ES.2017.22.31.30584 Text en This article is copyright of The Authors, 2017. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Roer, Louise
Hansen, Frank
Stegger, Marc
Sönksen, Ute Wolff
Hasman, Henrik
Hammerum, Anette M
Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014
title Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014
title_full Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014
title_fullStr Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014
title_full_unstemmed Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014
title_short Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014
title_sort novel mcr-3 variant, encoding mobile colistin resistance, in an st131 escherichia coli isolate from bloodstream infection, denmark, 2014
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553058/
http://dx.doi.org/10.2807/1560-7917.ES.2017.22.31.30584
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