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Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice

Asthma is a common disease in both high and lower income countries that starts early and persists often for life. A correct and accurate diagnosis, treatment and follow-up during childhood are essential for a better understanding of adult asthma and avoiding over- or under-treatment. Th2 inflammatio...

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Autores principales: Sánchez-García, Silvia, Habernau Mena, Alicia, Quirce, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553097/
https://www.ncbi.nlm.nih.gov/pubmed/28815006
http://dx.doi.org/10.1080/20018525.2017.1356160
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author Sánchez-García, Silvia
Habernau Mena, Alicia
Quirce, Santiago
author_facet Sánchez-García, Silvia
Habernau Mena, Alicia
Quirce, Santiago
author_sort Sánchez-García, Silvia
collection PubMed
description Asthma is a common disease in both high and lower income countries that starts early and persists often for life. A correct and accurate diagnosis, treatment and follow-up during childhood are essential for a better understanding of adult asthma and avoiding over- or under-treatment. Th2 inflammation in children with asthma symptoms is usually assessed by measuring with serum total IgE, blood eosinophilia and FeNO levels that may help to predict asthma, particularly in those infants and young children in whom lung function tests are difficult to perform. FeNO measurement, compared to intra-individual levels, may be useful also for ascertaining treatment adherence. Nevertheless, an isolated measurement may be insufficient and only the combination of these markers improves the diagnosis, phenotyping and follow-up of an asthmatic child.
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spelling pubmed-55530972017-08-16 Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice Sánchez-García, Silvia Habernau Mena, Alicia Quirce, Santiago Eur Clin Respir J Review Article Asthma is a common disease in both high and lower income countries that starts early and persists often for life. A correct and accurate diagnosis, treatment and follow-up during childhood are essential for a better understanding of adult asthma and avoiding over- or under-treatment. Th2 inflammation in children with asthma symptoms is usually assessed by measuring with serum total IgE, blood eosinophilia and FeNO levels that may help to predict asthma, particularly in those infants and young children in whom lung function tests are difficult to perform. FeNO measurement, compared to intra-individual levels, may be useful also for ascertaining treatment adherence. Nevertheless, an isolated measurement may be insufficient and only the combination of these markers improves the diagnosis, phenotyping and follow-up of an asthmatic child. Taylor & Francis 2017-08-09 /pmc/articles/PMC5553097/ /pubmed/28815006 http://dx.doi.org/10.1080/20018525.2017.1356160 Text en © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sánchez-García, Silvia
Habernau Mena, Alicia
Quirce, Santiago
Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice
title Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice
title_full Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice
title_fullStr Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice
title_full_unstemmed Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice
title_short Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice
title_sort biomarkers in inflammometry pediatric asthma: utility in daily clinical practice
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553097/
https://www.ncbi.nlm.nih.gov/pubmed/28815006
http://dx.doi.org/10.1080/20018525.2017.1356160
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