An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy

It is important to find better treatments for diabetic nephropathy (DN), a debilitating renal complication. Targeting early features of DN, including renal extracellular matrix accumulation (ECM) and glomerular hypertrophy, can prevent disease progression. Here we show that a megacluster of nearly 4...

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Detalles Bibliográficos
Autores principales: Kato, Mitsuo, Wang, Mei, Chen, Zhuo, Bhatt, Kirti, Oh, Hyung Jung, Lanting, Linda, Deshpande, Supriya, Jia, Ye, Lai, Jennifer Y.C., O’Connor, Christopher L., Wu, YiFan, Hodgin, Jeffrey B., Nelson, Robert G., Bitzer, Markus, Natarajan, Rama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553130/
https://www.ncbi.nlm.nih.gov/pubmed/27686049
http://dx.doi.org/10.1038/ncomms12864

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