Cargando…
Ovine recombinant PrP as an inhibitor of ruminant prion propagation in vitro
Prion diseases are fatal and incurable neurodegenerative diseases of humans and animals. Despite years of research, no therapeutic agents have been developed that can effectively manage or reverse disease progression. Recently it has been identified that recombinant prion proteins (rPrP) expressed i...
Autores principales: | Workman, Rob G., Maddison, Ben C., Gough, Kevin C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553304/ https://www.ncbi.nlm.nih.gov/pubmed/28665745 http://dx.doi.org/10.1080/19336896.2017.1342919 |
Ejemplares similares
-
Recombinant ovine prion protein can be mutated at position 136 to improve its efficacy as an inhibitor of prion propagation
por: Kopycka, Katarzyna, et al.
Publicado: (2023) -
Mammalian prion propagation in PrP transgenic Drosophila
por: Thackray, Alana M, et al.
Publicado: (2018) -
Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrP(Sc) over time
por: Maddison, Ben C, et al.
Publicado: (2015) -
Genetic modulation of CWD prion propagation in cervid PrP Drosophila
por: Thackray, Alana M., et al.
Publicado: (2023) -
In vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation
por: Thorne, Leigh, et al.
Publicado: (2012)