Cargando…

Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement

The fox tapeworm Echinococcus multilocularis causes human alveolar echinococcosis, commonly affecting the liver. However, in ∼1% of cases, systematic spread of the disease involves the brain as well. A patient had a 6-year history of liver and lung alveolar echinococcosis that was considered not sui...

Descripción completa

Detalles Bibliográficos
Autores principales: Kvascevicius, Robertas, Lapteva, Ona, Awar, Omar Al, Audronyte, Egle, Neverauskiene, Laura, Kvasceviciene, Eleonora, Sokolovas, Vitalijus, Strupas, Kestutis, Marcinkute, Audrone, Deplazes, Peter, Müllhaupt, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553476/
https://www.ncbi.nlm.nih.gov/pubmed/28824996
http://dx.doi.org/10.1055/s-0036-1592122
_version_ 1783256625973297152
author Kvascevicius, Robertas
Lapteva, Ona
Awar, Omar Al
Audronyte, Egle
Neverauskiene, Laura
Kvasceviciene, Eleonora
Sokolovas, Vitalijus
Strupas, Kestutis
Marcinkute, Audrone
Deplazes, Peter
Müllhaupt, Beat
author_facet Kvascevicius, Robertas
Lapteva, Ona
Awar, Omar Al
Audronyte, Egle
Neverauskiene, Laura
Kvasceviciene, Eleonora
Sokolovas, Vitalijus
Strupas, Kestutis
Marcinkute, Audrone
Deplazes, Peter
Müllhaupt, Beat
author_sort Kvascevicius, Robertas
collection PubMed
description The fox tapeworm Echinococcus multilocularis causes human alveolar echinococcosis, commonly affecting the liver. However, in ∼1% of cases, systematic spread of the disease involves the brain as well. A patient had a 6-year history of liver and lung alveolar echinococcosis that was considered not suitable for surgery, and treatment with albendazole was introduced. After the appearance of neurologic disturbances, an intracranial mass lesion was demonstrated by radiologic imaging. The lesion was surgically removed, and histologic analysis revealed metacestode tissue of E. multilocularis . Despite the surgical resection of the lesion, the patient died of progression of systemic alveolar echinococcosis. The authors highly recommend implementing neurologic monitoring to the follow-up algorithm for patients with systemically disseminated alveolar echinococcosis. When neurologic symptoms occur, radiologic imaging of the brain should be obtained immediately. Surgery should be considered for all intracranial echinococcal lesions, unless the lesion is located in the eloquent brain area.
format Online
Article
Text
id pubmed-5553476
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Thieme Medical Publishers
record_format MEDLINE/PubMed
spelling pubmed-55534762017-08-18 Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement Kvascevicius, Robertas Lapteva, Ona Awar, Omar Al Audronyte, Egle Neverauskiene, Laura Kvasceviciene, Eleonora Sokolovas, Vitalijus Strupas, Kestutis Marcinkute, Audrone Deplazes, Peter Müllhaupt, Beat Surg J (N Y) The fox tapeworm Echinococcus multilocularis causes human alveolar echinococcosis, commonly affecting the liver. However, in ∼1% of cases, systematic spread of the disease involves the brain as well. A patient had a 6-year history of liver and lung alveolar echinococcosis that was considered not suitable for surgery, and treatment with albendazole was introduced. After the appearance of neurologic disturbances, an intracranial mass lesion was demonstrated by radiologic imaging. The lesion was surgically removed, and histologic analysis revealed metacestode tissue of E. multilocularis . Despite the surgical resection of the lesion, the patient died of progression of systemic alveolar echinococcosis. The authors highly recommend implementing neurologic monitoring to the follow-up algorithm for patients with systemically disseminated alveolar echinococcosis. When neurologic symptoms occur, radiologic imaging of the brain should be obtained immediately. Surgery should be considered for all intracranial echinococcal lesions, unless the lesion is located in the eloquent brain area. Thieme Medical Publishers 2016-09-04 /pmc/articles/PMC5553476/ /pubmed/28824996 http://dx.doi.org/10.1055/s-0036-1592122 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Kvascevicius, Robertas
Lapteva, Ona
Awar, Omar Al
Audronyte, Egle
Neverauskiene, Laura
Kvasceviciene, Eleonora
Sokolovas, Vitalijus
Strupas, Kestutis
Marcinkute, Audrone
Deplazes, Peter
Müllhaupt, Beat
Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement
title Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement
title_full Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement
title_fullStr Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement
title_full_unstemmed Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement
title_short Fatal Liver and Lung Alveolar Echinococcosis with Newly Developed Neurologic Symptoms due to the Brain Involvement
title_sort fatal liver and lung alveolar echinococcosis with newly developed neurologic symptoms due to the brain involvement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553476/
https://www.ncbi.nlm.nih.gov/pubmed/28824996
http://dx.doi.org/10.1055/s-0036-1592122
work_keys_str_mv AT kvasceviciusrobertas fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT laptevaona fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT awaromaral fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT audronyteegle fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT neverauskienelaura fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT kvascevicieneeleonora fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT sokolovasvitalijus fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT strupaskestutis fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT marcinkuteaudrone fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT deplazespeter fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement
AT mullhauptbeat fatalliverandlungalveolarechinococcosiswithnewlydevelopedneurologicsymptomsduetothebraininvolvement