The pattern of KRAS mutations in metastatic colorectal cancer: a retrospective audit from Sri Lanka

OBJECTIVE: Activating mutations in the KRAS gene, found in approximately 53% of metastatic colorectal cancer (mCRC) cases, can render epidermal growth factor receptor (EGFR) inhibitors ineffective. Regional differences in these mutations have been reported. This is the first study which aims to desc...

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Detalles Bibliográficos
Autores principales: Sirisena, Nirmala Dushyanthi, Deen, Kemal, Mandawala, Dayupathi Eranda Nipunika, Herath, Pumindu, Dissanayake, Vajira Harshadeva Weerabaddana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553606/
https://www.ncbi.nlm.nih.gov/pubmed/28797274
http://dx.doi.org/10.1186/s13104-017-2731-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553606/
https://www.ncbi.nlm.nih.gov/pubmed/28797274
http://dx.doi.org/10.1186/s13104-017-2731-5

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