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Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model

BACKGROUND: Cancer cell invasion, dissemination, and metastasis have been linked to an epithelial-mesenchymal transition (EMT) of individual tumour cells. During EMT, adhesion molecules like E-cadherin are downregulated and the decrease of cell-cell adhesion allows tumour cells to dissociate from th...

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Detalles Bibliográficos
Autores principales:	Reher, David, Klink, Barbara, Deutsch, Andreas, Voss-Böhme, Anja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553611/ https://www.ncbi.nlm.nih.gov/pubmed/28800767 http://dx.doi.org/10.1186/s13062-017-0188-z

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