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Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure

The effects of retinoids on adrenal aldosterone synthase gene (CYP11B2) expression and aldosterone secretion are still unknown. We therefore examined the effects of nuclear retinoid X receptor (RXR) pan-agonist PA024 on CYP11B2 expression, aldosterone secretion and blood pressure, to elucidate its p...

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Detalles Bibliográficos
Autores principales: Suzuki, Dai, Saito-Hakoda, Akiko, Ito, Ryo, Shimizu, Kyoko, Parvin, Rehana, Shimada, Hiroki, Noro, Erika, Suzuki, Susumu, Fujiwara, Ikuma, Kagechika, Hiroyuki, Rainey, William E., Kure, Shigeo, Ito, Sadayoshi, Yokoyama, Atsushi, Sugawara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553648/
https://www.ncbi.nlm.nih.gov/pubmed/28800627
http://dx.doi.org/10.1371/journal.pone.0181055