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Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)

BACKGROUND: Pancreatic cancer is susceptible to gemcitabine resistance, and patients receive less benefit from gemcitabine chemotherapy. Previous studies report that gambogic acid possesses antineoplastic properties; however, to our knowledge, there have been no specific studies on its effects in pa...

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Detalles Bibliográficos
Autores principales:	Xia, Guanggai, Wang, Hongcheng, Song, Ziliang, Meng, Qingcai, Huang, Xiuyan, Huang, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553806/ https://www.ncbi.nlm.nih.gov/pubmed/28797284 http://dx.doi.org/10.1186/s13046-017-0579-0

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