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Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases
MPTP-mouse model constitutes a well-known model of neuroinflammation and mitochondrial failure occurring in Parkinson’s disease (PD). Although it has been extensively reported that nitric oxide (NO(●)) plays a key role in the pathogenesis of PD, the relative roles of nitric oxide synthase isoforms i...
Autores principales: | López, Ana, Ortiz, Francisco, Doerrier, Carolina, Venegas, Carmen, Fernández-Ortiz, Marisol, Aranda, Paula, Díaz-Casado, María E., Fernández-Gil, Beatriz, Barriocanal-Casado, Eliana, Escames, Germaine, López, Luis C., Acuña-Castroviejo, Darío |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553810/ https://www.ncbi.nlm.nih.gov/pubmed/28800639 http://dx.doi.org/10.1371/journal.pone.0183090 |
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