The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

BACKGROUND: Glioblastoma (GBM) is a highly migratory, invasive, and angiogenic brain tumor. Like vascular endothelial growth factor-A (VEGF-A), placental growth factor (PlGF) promotes GBM angiogenesis. VEGF-A is a ligand for both VEGF receptor-1 (VEGFR-1) and VEGFR-2, while PlGF interacts exclusivel...

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Detalles Bibliográficos
Autores principales: Atzori, Maria Grazia, Tentori, Lucio, Ruffini, Federica, Ceci, Claudia, Lisi, Lucia, Bonanno, Elena, Scimeca, Manuel, Eskilsson, Eskil, Daubon, Thomas, Miletic, Hrvoje, Ricci Vitiani, Lucia, Pallini, Roberto, Navarra, Pierluigi, Bjerkvig, Rolf, D’Atri, Stefania, Lacal, Pedro Miguel, Graziani, Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553938/
https://www.ncbi.nlm.nih.gov/pubmed/28797294
http://dx.doi.org/10.1186/s13046-017-0577-2

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