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Prolonged Pemetrexed Infusion Plus Gemcitabine in Refractory Metastatic Colorectal Cancer: Preclinical Rationale and Phase II Study Results

LESSONS LEARNED. Difficulties in translating in vitro results into clinical practice are inevitable. Further efforts to verify the efficacy of alternative schedules of pemetrexed in solid tumors are encouraged. BACKGROUND. We investigated the cytotoxic activity of pemetrexed in combination with seve...

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Detalles Bibliográficos
Autores principales: Passardi, Alessandro, Fanini, Francesca, Turci, Livia, Foca, Flavia, Rosetti, Paola, Ruscelli, Silvia, Casadei Gardini, Andrea, Valgiusti, Martina, Dazzi, Claudio, Marangolo, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553965/
https://www.ncbi.nlm.nih.gov/pubmed/28592624
http://dx.doi.org/10.1634/theoncologist.2017-0206