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Differential Effects of Linagliptin on the Function of Human Islets Isolated from Non-diabetic and Diabetic Donors

Linagliptin is a dipeptidyl Peptidase-4 (DPP-4) inhibitor that inhibits the degradation of glucagon-like peptide 1 (GLP-1), and has been approved for the treatment of type 2 diabetes (T2D) in clinic. Previous studies have shown linagliptin improves β cell function using animal models and isolated is...

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Detalles Bibliográficos
Autores principales:	Zhang, Yanqing, Wu, Meifen, Htun, Wynn, Dong, Emily W., Mauvais-Jarvis, Franck, Fonseca, Vivian A., Wu, Hongju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554162/ https://www.ncbi.nlm.nih.gov/pubmed/28801559 http://dx.doi.org/10.1038/s41598-017-08271-9

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