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Statistical characterization of therapeutic protein modifications

Peptide mapping with liquid chromatography–tandem mass spectrometry (LC-MS/MS) is an important analytical method for characterization of post-translational and chemical modifications in therapeutic proteins. Despite its importance, there is currently no consensus on the statistical analysis of the r...

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Detalles Bibliográficos
Autores principales: Tsai, Tsung-Heng, Hao, Zhiqi, Hong, Qiuting, Moore, Benjamin, Stella, Cinzia, Zhang, Jeffrey H., Chen, Yan, Kim, Michael, Koulis, Theo, Ryslik, Gregory A., Verschueren, Erik, Jacobson, Fred, Haskins, William E., Vitek, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554216/
https://www.ncbi.nlm.nih.gov/pubmed/28801661
http://dx.doi.org/10.1038/s41598-017-08333-y