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CK2 is a key regulator of SLC4A2-mediated Cl(−)/HCO(3)(−) exchange in human airway epithelia
Transepithelial bicarbonate secretion by human airway submucosal glands and surface epithelial cells is crucial to maintain the pH-sensitive innate defence mechanisms of the lung. cAMP agonists stimulate HCO(3) (−) secretion via coordinated increases in basolateral HCO(3) (−) influx and accumulation...
Autores principales: | Ibrahim, Salam H., Turner, Mark J., Saint-Criq, Vinciane, Garnett, James, Haq, Iram J., Brodlie, Malcolm, Ward, Chris, Borgo, Christian, Salvi, Mauro, Venerando, Andrea, Gray, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554290/ https://www.ncbi.nlm.nih.gov/pubmed/28455748 http://dx.doi.org/10.1007/s00424-017-1981-3 |
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