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Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus
Epstein-Barr virus (EBV) infection is associated with tumours such as Burkitt lymphoma, nasopharyngeal carcinoma, and gastric cancer. We previously showed that EBV(+) gastric cancer presents an extremely high-methylation epigenotype and this aberrant DNA methylation causes silencing of multiple tumo...
Autores principales: | Okabe, Atsushi, Funata, Sayaka, Matsusaka, Keisuke, Namba, Hiroe, Fukuyo, Masaki, Rahmutulla, Bahityar, Oshima, Motohiko, Iwama, Atsushi, Fukayama, Masashi, Kaneda, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554293/ https://www.ncbi.nlm.nih.gov/pubmed/28801683 http://dx.doi.org/10.1038/s41598-017-08370-7 |
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