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Lysine-Directed Post-translational Modifications of Tau Protein in Alzheimer's Disease and Related Tauopathies

Tau is a microtubule-associated protein responsible mainly for stabilizing the neuronal microtubule network in the brain. Under normal conditions, tau is highly soluble and adopts an “unfolded” conformation. However, it undergoes conformational changes resulting in a less soluble form with weakened...

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Detalles Bibliográficos
Autores principales:	Kontaxi, Christiana, Piccardo, Pedro, Gill, Andrew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554484/ https://www.ncbi.nlm.nih.gov/pubmed/28848737 http://dx.doi.org/10.3389/fmolb.2017.00056

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