Mycobacterium bovis Bacillus Calmette–Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function

Intralesional Mycobacterium bovis bacillus Calmette–Guérin (BCG) has long been a relatively inexpensive therapy for inoperable cutaneous metastatic melanoma (CMM), although intralesional BCG skin mechanisms remain understudied. We analyzed intralesional BCG-treated CMM lesions combined with in vitro...

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Detalles Bibliográficos
Autores principales: Lardone, Ricardo D., Chan, Alfred A., Lee, Agnes F., Foshag, Leland J., Faries, Mark B., Sieling, Peter A., Lee, Delphine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554507/
https://www.ncbi.nlm.nih.gov/pubmed/28848560
http://dx.doi.org/10.3389/fimmu.2017.00965

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