MET18 Deficiency Increases the Sensitivity of Yeast to Oxidative Stress and Shortens Replicative Lifespan by Inhibiting Catalase Activity

Yeast MET18, a subunit of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery which is responsible for the maturation of Fe/S proteins, has been reported to participate in the oxidative stress response. However, the underlying molecular mechanisms remain unclear. In this study, we cons...

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Detalles Bibliográficos
Autores principales: Chen, Ya-qin, Liu, Xin-guang, Zhao, Wei, Cui, Hongjing, Ruan, Jie, Yuan, Yuan, Tu, Zhiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554550/
https://www.ncbi.nlm.nih.gov/pubmed/28828388
http://dx.doi.org/10.1155/2017/7587395

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