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Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation

Fast excitatory transmission in the CNS is mediated mainly by AMPA-type glutamate receptors (AMPARs) associated with transmembrane AMPAR regulatory proteins (TARPs). At the high glutamate concentrations typically seen during synaptic transmission, TARPs slow receptor desensitization and enhance mean...

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Detalles Bibliográficos
Autores principales:	Coombs, Ian D., MacLean, David M., Jayaraman, Vasanthi, Farrant, Mark, Cull-Candy, Stuart G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554777/ https://www.ncbi.nlm.nih.gov/pubmed/28768197 http://dx.doi.org/10.1016/j.celrep.2017.07.014

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