Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

The mouse inner cell mass (ICM) segregates into the epiblast and primitive endoderm (PrE) lineages coincident with implantation of the embryo. The epiblast subsequently undergoes considerable expansion of cell numbers prior to gastrulation. To investigate underlying regulatory principles, we perform...

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Detalles Bibliográficos
Autores principales: Mohammed, Hisham, Hernando-Herraez, Irene, Savino, Aurora, Scialdone, Antonio, Macaulay, Iain, Mulas, Carla, Chandra, Tamir, Voet, Thierry, Dean, Wendy, Nichols, Jennifer, Marioni, John C., Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554778/
https://www.ncbi.nlm.nih.gov/pubmed/28768204
http://dx.doi.org/10.1016/j.celrep.2017.07.009

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