The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription

Small RNAs play a crucial role in genome defense against transposable elements and guide Argonaute proteins to nascent RNA transcripts to induce co-transcriptional gene silencing. However, the molecular basis of this process remains unknown. Here, we identify the conserved RNA helicase Aquarius/EMB-...

Descripción completa

Detalles Bibliográficos
Autores principales: Akay, Alper, Di Domenico, Tomas, Suen, Kin M., Nabih, Amena, Parada, Guillermo E., Larance, Mark, Medhi, Ragini, Berkyurek, Ahmet C., Zhang, Xinlian, Wedeles, Christopher J., Rudolph, Konrad L.M., Engelhardt, Jan, Hemberg, Martin, Ma, Ping, Lamond, Angus I., Claycomb, Julie M., Miska, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554785/
https://www.ncbi.nlm.nih.gov/pubmed/28787591
http://dx.doi.org/10.1016/j.devcel.2017.07.002

Ejemplares similares

Ejemplares similares