The idiosyncratic drug-induced gene expression changes in HepG2 cells

The inflammatory stress has been associated with an increase in susceptibility to idiosyncratic drug-induced liver injury (DILI). However, the molecular mechanisms of this inflammation-associated idiosyncratic drug hepatotoxicity remain unknown. We exposed HepG2 cells with high and low doses of thre...

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Detalles Bibliográficos
Autores principales: Jiang, J., Mathijs, K., Timmermans, L., Claessen, S.M., Hecka, A., Weusten, J., Peters, R., van Delft, J.H., Kleinjans, J.C.S., Jennen, D.G.J., de Kok, T.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Pharmacology, Toxicology and Pharmaceutical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554930/
https://www.ncbi.nlm.nih.gov/pubmed/28831409
http://dx.doi.org/10.1016/j.dib.2017.07.074

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