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Mechanism of pathogen recognition by human dectin-2

Dectin-2, a C-type lectin on macrophages and other cells of the innate immune system, functions in response to pathogens, particularly fungi. The carbohydrate-recognition domain (CRD) in dectin-2 is linked to a transmembrane sequence that interacts with the common Fc receptor γ subunit to initiate i...

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Detalles Bibliográficos
Autores principales:	Feinberg, Hadar, Jégouzo, Sabine A. F., Rex, Maximus J., Drickamer, Kurt, Weis, William I., Taylor, Maureen E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555199/ https://www.ncbi.nlm.nih.gov/pubmed/28652405 http://dx.doi.org/10.1074/jbc.M117.799080

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