Mechanically Induced Ectopy via Stretch-Activated Cation-Nonselective Channels Is Caused by Local Tissue Deformation and Results in Ventricular Fibrillation if Triggered on the Repolarization Wave Edge (Commotio Cordis)

BACKGROUND—: External chest impacts (commotio cordis) can cause mechanically induced premature ventricular excitation (PVE(M)) and, rarely, ventricular fibrillation (VF). Because block of stretch-sensitive ATP-inactivated potassium channels curtailed VF occurrence in a porcine model of commotio cord...

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Detalles Bibliográficos
Autores principales: Quinn, T. Alexander, Jin, Honghua, Lee, Peter, Kohl, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555388/
https://www.ncbi.nlm.nih.gov/pubmed/28794084
http://dx.doi.org/10.1161/CIRCEP.116.004777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555388/
https://www.ncbi.nlm.nih.gov/pubmed/28794084
http://dx.doi.org/10.1161/CIRCEP.116.004777

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