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The Accuracy and Bias of Single-Step Genomic Prediction for Populations Under Selection

In single-step analyses, missing genotypes are explicitly or implicitly imputed, and this requires centering the observed genotypes using the means of the unselected founders. If genotypes are only available for selected individuals, centering on the unselected founder mean is not straightforward. H...

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Detalles Bibliográficos
Autores principales: Hsu, Wan-Ling, Garrick, Dorian J., Fernando, Rohan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555473/
https://www.ncbi.nlm.nih.gov/pubmed/28642364
http://dx.doi.org/10.1534/g3.117.043596