Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat

CASE SUMMARY: A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE). The cat’s clinical signs resolved, but 6 months la...

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Autores principales: Heaps, Laura A, Scudder, Christopher J, Lipscomb, Vicky J, Steinbach, Sarah ML, Priestnall, Simon L, Martineau, Henny, Szladovits, Balazs, Fowkes, Robert C, Garden, Oliver A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555519/
https://www.ncbi.nlm.nih.gov/pubmed/28839946
http://dx.doi.org/10.1177/2055116917722701
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author Heaps, Laura A
Scudder, Christopher J
Lipscomb, Vicky J
Steinbach, Sarah ML
Priestnall, Simon L
Martineau, Henny
Szladovits, Balazs
Fowkes, Robert C
Garden, Oliver A
author_facet Heaps, Laura A
Scudder, Christopher J
Lipscomb, Vicky J
Steinbach, Sarah ML
Priestnall, Simon L
Martineau, Henny
Szladovits, Balazs
Fowkes, Robert C
Garden, Oliver A
author_sort Heaps, Laura A
collection PubMed
description CASE SUMMARY: A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE). The cat’s clinical signs resolved, but 6 months later it was diagnosed as having an anaplastic astrocytoma and was euthanased. Serum anti-Müllerian hormone (AMH) concentration prior to OHE was increased vs a control group of entire and neutered female cats. Following OHE, serum AMH concentration decreased to <1% of the original value. RELEVANCE AND NOVEL INFORMATION: Serum AMH measurement may represent a novel diagnostic and monitoring tool for functional ovarian neoplasms in cats.
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spelling pubmed-55555192017-08-24 Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat Heaps, Laura A Scudder, Christopher J Lipscomb, Vicky J Steinbach, Sarah ML Priestnall, Simon L Martineau, Henny Szladovits, Balazs Fowkes, Robert C Garden, Oliver A JFMS Open Rep Case Report CASE SUMMARY: A 15-year-old female cat was presented for investigation of progressive behavioural changes, polyuria, polydipsia and periuria. An ovarian granulosa cell tumour was identified and the cat underwent therapeutic ovariohysterectomy (OHE). The cat’s clinical signs resolved, but 6 months later it was diagnosed as having an anaplastic astrocytoma and was euthanased. Serum anti-Müllerian hormone (AMH) concentration prior to OHE was increased vs a control group of entire and neutered female cats. Following OHE, serum AMH concentration decreased to <1% of the original value. RELEVANCE AND NOVEL INFORMATION: Serum AMH measurement may represent a novel diagnostic and monitoring tool for functional ovarian neoplasms in cats. SAGE Publications 2017-08-10 /pmc/articles/PMC5555519/ /pubmed/28839946 http://dx.doi.org/10.1177/2055116917722701 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Heaps, Laura A
Scudder, Christopher J
Lipscomb, Vicky J
Steinbach, Sarah ML
Priestnall, Simon L
Martineau, Henny
Szladovits, Balazs
Fowkes, Robert C
Garden, Oliver A
Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
title Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
title_full Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
title_fullStr Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
title_full_unstemmed Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
title_short Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
title_sort serum anti-müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555519/
https://www.ncbi.nlm.nih.gov/pubmed/28839946
http://dx.doi.org/10.1177/2055116917722701
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