A GDF15 3′ UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p

Growth differentiation factor 15 (GDF15) is a strong predictor of cardiovascular events and mortality in individuals with or without cardiovascular diseases. Single nucleotide polymorphisms (SNPs) in microRNA (miRNA) target sites, also known as miRSNPs, are known to enhance or weaken miRNA-mRNA inte...

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Detalles Bibliográficos
Autores principales: Teng, Ming-Sheng, Hsu, Lung-An, Juan, Shu-Hui, Lin, Wen-Chi, Lee, Ming-Cheng, Su, Cheng-Wen, Wu, Semon, Ko, Yu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555568/
https://www.ncbi.nlm.nih.gov/pubmed/28806401
http://dx.doi.org/10.1371/journal.pone.0183187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555568/
https://www.ncbi.nlm.nih.gov/pubmed/28806401
http://dx.doi.org/10.1371/journal.pone.0183187

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