Activation of p53, inhibition of telomerase activity and induction of estrogen receptor beta are associated with the anti-growth effects of combination of ovarian hormones and retinoids in immortalized human mammary epithelial cells

BACKGROUND: A full-term pregnancy has been associated with reduced risk for developing breast cancer. In rodent models, the protective effect of pregnancy can be mimicked with a defined regimen of estrogen and progesterone combination (E/P). However, the effects of pregnancy levels of E/P in humans...

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Detalles Bibliográficos
Autores principales: Zhang, Jiahui, Tu, Yifan, Smith-Schneider, Sallie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555559/
https://www.ncbi.nlm.nih.gov/pubmed/15755327
http://dx.doi.org/10.1186/1475-2867-5-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC555559/
https://www.ncbi.nlm.nih.gov/pubmed/15755327
http://dx.doi.org/10.1186/1475-2867-5-6

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