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Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

Rickettsial infections continue to cause serious morbidity and mortality in severe human cases around the world. Host cell adhesion and invasion is an essential requisite for intracellular growth, replication, and subsequent dissemination of pathogenic rickettsiae. Heparan sulfate proteoglycans [HSP...

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Detalles Bibliográficos
Autores principales: Sahni, Abha, Patel, Jignesh, Narra, Hema P., Schroeder, Casey L. C., Walker, David H., Sahni, Sanjeev K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555671/
https://www.ncbi.nlm.nih.gov/pubmed/28806774
http://dx.doi.org/10.1371/journal.pone.0183181