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Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)

GPR116 (ADGRF5) and ELTD1 (ADGRL4) belong to different subfamilies of the adhesion G-protein-coupled receptor group but are both expressed in endothelial cells. We therefore analyzed their functions in mice lacking these receptors. While loss of GPR116 or ELTD1 alone had no obvious effect on cardiov...

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Detalles Bibliográficos
Autores principales:	Lu, Shun, Liu, Shuya, Wietelmann, Astrid, Kojonazarov, Baktybek, Atzberger, Ann, Tang, Cong, Schermuly, Ralph Theo, Gröne, Hermann-Josef, Offermanns, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555693/ https://www.ncbi.nlm.nih.gov/pubmed/28806758 http://dx.doi.org/10.1371/journal.pone.0183166

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