Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit

BACKGROUND: Enhanced platelet-derived growth factor receptor α (PDGFRα) signaling pathway activity leads to cardiac fibrosis. However, because of the pleiotropic effects of PDGFR signaling, its role in mediating the cardiac fibrotic response remains poorly understood. This study aimed to investigate...

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Detalles Bibliográficos
Autores principales: Wang, Lexun, Yue, Yuan, Yang, Xiao, Fan, Tian, Mei, Bo, Hou, Jian, Liang, Mengya, Chen, Guangxian, Wu, Zhongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555739/
https://www.ncbi.nlm.nih.gov/pubmed/28780584
http://dx.doi.org/10.12659/MSM.906038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555739/
https://www.ncbi.nlm.nih.gov/pubmed/28780584
http://dx.doi.org/10.12659/MSM.906038

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